BDBM478992 (R)-N-(4-(3-((5-chloropyrimidin-2- yl)amino)pyrrolidine-1-carbonyl)-3- methylphenyl)acrylamide::US10894788, Example 32::US11390618, Example 32

SMILES Cc1cc(NC(=O)C=C)ccc1C(=O)N1CC[C@H](C1)Nc1ncc(Cl)cn1

InChI Key InChIKey=LMESFSCXDXXDRB-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478992   

TargetCyclin-dependent kinase 12(Homo sapiens)
Kinnate Biopharma

US Patent
LigandPNGBDBM478992((R)-N-(4-(3-((5-chloropyrimidin-2- yl)amino)pyrrol...)
Affinity DataIC50:  550nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent